Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Operating activities
Net loss	$ (72,891)	$ (51,834)
Reconciliation of net loss to net cash used in operating activities:
Stock-based compensation expense	6,314	4,554
Net gain on warrants inherited in acquisition of Quellis		1,542
Right-of-use asset - operating lease	585	(554)
Other non-cash items	(40)	112
Changes in assets and liabilities:
Prepaid expenses and other assets	(4,546)	(1,568)
Lease liability - operating lease	(610)	574
Accounts payable	725	(766)
Accrued expenses	2,018	4,407
Net cash used in operating activities	(68,445)	(43,533)
Investing activities
Purchases of short-term investments	(1,924,423)	(396,064)
Sales and maturities of short-term investments	2,059,500	229,026
Purchases of property and equipment	(25)	(91)
Net cash provided by (used in) investing activities	135,052	(167,129)
Financing activities
Proceeds from public offering, net of underwriting discounts and issuance costs	59,480	107,646
Proceeds from at-the-market offering, net of issuance costs	28,498	36,991
Proceeds from exercise of stock options and warrants	420	84
Net cash provided by financing activities	88,398	144,721
Net increase (decrease) in cash, cash equivalents and restricted cash	155,005	(65,941)
Cash, cash equivalents and restricted cash, beginning of period	20,688	86,629
Cash, cash equivalents and restricted cash, end of period	175,693	20,688
Supplemental disclosure of non-cash investing and financing activities:
Operating lease right-of-use assets obtained in exchange for operating lease liabilities		1,268
Conversion of Series X Preferred Stock into common stock	1,074
Purchases of property and equipment in accounts payable and accrued liabilities	17
Public offering issuance costs in accrued expenses	$ 120	$ 100