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Income Taxes - Deferred tax assets (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Deferred tax assets    
Net operating loss carryforwards $ 85,734 $ 80,136
Tax credit carryforwards 14,576 12,073
Capitalized research and development 16,927 8,094
Capitalized licenses 4,041  
Capitalized legal expenses 918 964
Lease liability 90 257
Other differences 2,587 2,365
Total gross deferred tax assets 124,873 103,889
Less valuation allowance (124,774) (103,630)
Net deferred tax assets 99 259
Deferred tax liabilities    
ROU asset (99) (259)
Net deferred taxes 0 0
Deferred tax assets research and development 16,900 8,100
Increase in valuation allowance $ 21,100 $ 14,600