Reserved for Future Issuance (Details) - shares	Mar. 31, 2023	Dec. 31, 2022
Stockholders' Equity
Number of shares reserved for future issuance	9,903,950	10,076,610
Series X Preferred Stock
Stockholders' Equity
Number of shares reserved for future issuance	5,184,591	5,242,501
Options outstanding to purchase common stock
Stockholders' Equity
Number of shares reserved for future issuance	2,562,234	2,253,431
Reserve under the 2015 Stock Incentive Plan and the 2022 Inducement Stock Incentive Plan
Stockholders' Equity
Number of shares reserved for future issuance	1,082,245	1,013,520
Warrants for the purchase of common stock
Stockholders' Equity
Number of shares reserved for future issuance	1,031,820	1,530,176
Shares reserved for the employee stock purchase plan
Stockholders' Equity
Number of shares reserved for future issuance	43,060	36,982