Stockholders' Equity - Shares Reserved for Future Issuance (Details) - shares	Dec. 31, 2022	Dec. 31, 2021
Stockholders' Equity
Number of shares reserved for future issuance	10,076,610	9,784,254
Series X Preferred Stock
Stockholders' Equity
Number of shares reserved for future issuance	5,242,501	5,242,501
Warrants for the purchase of common stock
Stockholders' Equity
Number of shares reserved for future issuance	1,530,176	1,530,380
Options outstanding to purchase common stock
Stockholders' Equity
Number of shares reserved for future issuance	2,253,431	1,346,733
Reserve under the 2015 Stock Incentive Plan and the 2022 Inducement Stock Incentive Plan
Stockholders' Equity
Number of shares reserved for future issuance	1,013,520	1,633,736
Shares reserved for the employee stock purchase plan
Stockholders' Equity
Number of shares reserved for future issuance	36,982	30,904