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Fair Value Measurements - Warrant liability (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2022
Jun. 02, 2021
Jan. 28, 2021
Financial Instruments Measurements        
Exercise price of warrants (in dollars per share)   $ 41.75    
Derivative warrant liability was valued based on significant inputs not observable in the market, which represents a Level 3        
Balance at beginning of year $ 0      
Issuance of warrants 4,332      
(Decrease) increase in the fair value of the warrants $ (864)      
(Decrease) increase in the fair value of the warrants, financial statement location Research and development      
Reclassification of warrant liability to additional paid in-capital $ (3,468)      
Ending balance $ 0      
Common stock        
Financial Instruments Measurements        
Number of shares which may be purchased with warrants   467,500 467,500  
Exercise price of warrants (in dollars per share)   $ 2.10 $ 2.10  
Quellis Biosciences, Inc | Series X Preferred Stock        
Financial Instruments Measurements        
Number of shares which may be purchased with warrants   2,805   2,805
Exercise price of warrants (in dollars per share)   $ 341.70   $ 341.70
Quellis Biosciences, Inc | Common stock        
Financial Instruments Measurements        
Number of shares which may be purchased with warrants       30,856
Exercise price of warrants (in dollars per share)       $ 2.10