Organization and Operations - Stock Purchase Agreement and Series X Preferred Stock (Details) $ in Thousands		1 Months Ended	12 Months Ended
	Jan. 28, 2021 USD ($) shares	Feb. 28, 2021 shares	Dec. 31, 2022 shares	Dec. 31, 2021 USD ($) shares	Jun. 02, 2021
Stock Purchase Agreement and Series X Preferred Stock
Beneficial conversion feature | $				$ 19,565
Common Stock Issuable Upon Conversion at Transaction Date		14,813,954
Common stock
Stock Purchase Agreement and Series X Preferred Stock
Number of common shares issued from conversion of series X preferred stock				9,103,664
Minimum
Stock Purchase Agreement and Series X Preferred Stock
Common stock, percentage of beneficial ownership initially, after conversion			4.99%
Common stock, percentage of beneficial ownership thereafter, after conversion			4.99%
Maximum
Stock Purchase Agreement and Series X Preferred Stock
Common stock, percentage of beneficial ownership initially, after conversion			9.99%
Common stock, percentage of beneficial ownership thereafter, after conversion			19.99%
Shares issued in merger
Stock Purchase Agreement and Series X Preferred Stock
Common Stock Issuable Upon Conversion at Transaction Date		8,417,502
Shares issued in February 2021 Financing
Stock Purchase Agreement and Series X Preferred Stock
Common Stock Issuable Upon Conversion at Transaction Date		5,928,952
Warrant assumed in merger
Stock Purchase Agreement and Series X Preferred Stock
Common Stock Issuable Upon Conversion at Transaction Date		467,500
Series X redeemable convertible preferred stock
Stock Purchase Agreement and Series X Preferred Stock
Issuance of preferred stock in a private offering of public equity, net of issuance costs (in shares)				35,573
Series X Preferred Stock at Transaction Date		88,882
Number of shares of common stock into which each share of series X preferred stock may be converted			166.67		166.67
Number of preferred shares converted during period			54,622
Number of common shares issued from conversion of series X preferred stock			9,103,664
Number of common shares issuable upon conversion of preferred stock (in shares)			5,242,501
Preferred stock, outstanding (in shares)			31,455	31,455
Series X redeemable convertible preferred stock | Common stock
Stock Purchase Agreement and Series X Preferred Stock
Number of common shares issued from conversion of series X preferred stock				(54,622)
Series X redeemable convertible preferred stock | Shares issued in merger
Stock Purchase Agreement and Series X Preferred Stock
Series X Preferred Stock at Transaction Date		50,504
Series X redeemable convertible preferred stock | Shares issued in February 2021 Financing
Stock Purchase Agreement and Series X Preferred Stock
Series X Preferred Stock at Transaction Date		35,573
Series X redeemable convertible preferred stock | Warrant assumed in merger
Stock Purchase Agreement and Series X Preferred Stock
Series X Preferred Stock at Transaction Date		2,805
Series X redeemable convertible preferred stock | Quellis Biosciences, Inc
Stock Purchase Agreement and Series X Preferred Stock
Number of shares of common stock into which each share of series X preferred stock may be converted	166.67
Series X redeemable convertible preferred stock | Quellis Biosciences, Inc | Stock Purchase Agreement
Stock Purchase Agreement and Series X Preferred Stock
Issuance of preferred stock in a private offering of public equity, net of issuance costs (in shares)	35,573
Gross proceeds from issuance of preferred stock in a private offering | $	$ 110,000
Net proceeds from issuance of private placement | $	104,300
Beneficial conversion feature | $	19,600
Issuance costs | $	$ 5,700
Number of shares of common stock into which each share of series X preferred stock may be converted	166.67