Organization and Operations - Reverse Stock Split, Agreement and Plan of Merger (Details) - USD ($) $ / shares in Units, $ in Millions			3 Months Ended
	Aug. 19, 2021	Jan. 28, 2021	Mar. 31, 2021	Jun. 30, 2022	Dec. 31, 2021	Jun. 02, 2021
Reverse Stock Split
Reverse stock split ratio	0.1667
Agreement and Plan of Merger
Common stock, par value (in dollars per share)				$ 0.001	$ 0.001
Series X redeemable convertible preferred stock
Agreement and Plan of Merger
Issuance of preferred stock and common stock upon acquisition of Quellis (in shares)			50,504
Common stock
Agreement and Plan of Merger
Issuance of preferred stock and common stock upon acquisition of Quellis(in shares)			555,444
Warrant or right to purchase number of shares						467,500
Exercise Price (in dollars per share)						$ 2.10
Quellis Biosciences, Inc | Series X redeemable convertible preferred stock
Agreement and Plan of Merger
Issuance of preferred stock and common stock upon acquisition of Quellis (in shares)		50,504
Conversion value on closing date		$ 122.7
Warrant or right to purchase number of shares		2,805
Exercise Price (in dollars per share)		$ 341.70
Quellis Biosciences, Inc | Common stock
Agreement and Plan of Merger
Issuance of preferred stock and common stock upon acquisition of Quellis(in shares)		555,444
Common stock, par value (in dollars per share)		$ 0.001
Number of options assumed in Quellis Acquisition		55,414
Warrant or right to purchase number of shares		30,856
Exercise Price (in dollars per share)		$ 2.10