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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Preferred Stock
Series X redeemable convertible preferred stock
Common Stock
Additional paid-in capital
Accumulated Deficit
Accumulated other comprehensive loss
Total
Balance, beginning of period at Dec. 31, 2019 $ 0 $ 12 $ 259,305 $ (223,597) $ 0  
Balance, beginning of period (in shares) at Dec. 31, 2019 0 12,433,600        
Increase (Decrease) in Shareholders' Equity            
Issuance of common stock in a public offering, net of issuance costs     24,554      
Issuance of common stock for at-the-market offerings   $ 2 7,328      
Issuance of common stock for at-the-market offerings (in shares)   1,100,001        
Issuance of common stock and warrants in public offerings   $ 5        
Issuance of common stock and warrants in public offerings (in shares)   5,290,000        
Stock-based compensation expense     710      
Net loss       (17,460)   $ (17,460)
Realized loss on short-term investments         1 1
Balance, end of period at Jun. 30, 2020   $ 19 291,897 (241,057) 1 50,860
Balance, end of period (in shares) at Jun. 30, 2020   18,823,601        
Balance, beginning of period at Mar. 31, 2020 $ 0 $ 18 285,257 (231,549) (15)  
Balance, beginning of period (in shares) at Mar. 31, 2020 0 17,897,172        
Increase (Decrease) in Shareholders' Equity            
Issuance of common stock for at-the-market offerings   $ 1 6,269      
Issuance of common stock for at-the-market offerings (in shares)   926,429        
Stock-based compensation expense     371      
Net loss       (9,508)   (9,508)
Realized loss on short-term investments         16 16
Balance, end of period at Jun. 30, 2020   $ 19 291,897 (241,057) $ 1 50,860
Balance, end of period (in shares) at Jun. 30, 2020   18,823,601        
Balance, beginning of period at Dec. 31, 2020 $ 0 $ 20 301,546 (260,897)   $ 40,669
Balance, beginning of period (in shares) at Dec. 31, 2020 0 20,084,337       20,084,337
Increase (Decrease) in Shareholders' Equity            
Reclassification of preferred stock to permanent equity $ 240,881          
Reclassification of preferred stock to permanent equity (in shares) 86,077          
Conversion of preferred stock into common stock $ (165,548)          
Conversion of preferred stock into common stock (in shares) (53,532)          
Issuance of preferred stock in a private offering of public equity, net of issuance costs     19,565      
Issuance of common stock upon acquisition of Quellis   $ 3 8,095      
Issuance of common stock upon acquisition of Quellis (in shares)   3,332,669        
Issuance of common stock upon the conversion of preferred stock   $ 54 165,495      
Issuance of common stock upon the conversion of preferred stock (in shares)   53,531,797        
Dividend on convertible preferred stock related to beneficial conversion feature and issuance costs $ 24,437   (24,437)      
Expense related to warrants inherited in acquisition of Quellis     387      
Reclassification of warrant liability to additional paid-in capital     3,468      
Stock-based compensation expense     1,380      
Net loss       (177,550)   $ (177,550)
Balance, end of period at Jun. 30, 2021 $ 99,770 $ 77 475,499 (438,447)   $ 136,899
Balance, end of period (in shares) at Jun. 30, 2021 32,545 76,948,803       76,948,803
Balance, beginning of period at Mar. 31, 2021 $ 0 $ 23 329,813 (430,981)    
Balance, beginning of period (in shares) at Mar. 31, 2021 0 23,417,006        
Increase (Decrease) in Shareholders' Equity            
Reclassification of preferred stock to permanent equity $ 240,881          
Reclassification of preferred stock to permanent equity (in shares) 86,077          
Conversion of preferred stock into common stock $ (165,548)          
Conversion of preferred stock into common stock (in shares) (53,532)          
Issuance of common stock upon the conversion of preferred stock   $ 54 165,495      
Issuance of common stock upon the conversion of preferred stock (in shares)   53,531,797        
Dividend on convertible preferred stock related to beneficial conversion feature and issuance costs $ 24,437   (24,437)      
Expense related to warrants inherited in acquisition of Quellis     146      
Reclassification of warrant liability to additional paid-in capital     3,468      
Stock-based compensation expense     1,014      
Net loss       (7,466)   $ (7,466)
Balance, end of period at Jun. 30, 2021 $ 99,770 $ 77 $ 475,499 $ (438,447)   $ 136,899
Balance, end of period (in shares) at Jun. 30, 2021 32,545 76,948,803       76,948,803