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Organization and Operations (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
Jan. 30, 2020
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Common Stock        
Common stock, par value (in dollars per share)   $ 0.001   $ 0.001
Accumulated deficit   $ (231,549)   $ (223,597)
Cash, cash equivalents and short-term investments   $ 55,100    
Common stock        
Common Stock        
Number of shares issued   173,572 353,746  
Gross proceeds from public offering   $ 1    
Common stock | Cowen        
Common Stock        
Percentage of commission paid to underwriter based on proceeds from common stock   3.00%    
Common stock | ATM        
Common Stock        
Number of shares issued   173,572    
Share price (in dollars per share)   $ 6.29    
Proceeds from public offering, net of issuance costs   $ 1,100    
Common stock | First ATM Program | Cowen        
Common Stock        
Remaining available under sales agreement   $ 43,600    
Common stock | Over-Allotment option for underwriters | Oppenheimer & Co. Inc        
Common Stock        
Number of shares issued 690,000      
Common stock | January 2020 Financing | Oppenheimer & Co. Inc        
Common Stock        
Number of shares issued 5,290,000      
Share price (in dollars per share) $ 5.00      
Gross proceeds from public offering $ 26,500      
Proceeds from public offering, net of issuance costs $ 24,600