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Stock Incentive Plans (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Shares          
Outstanding, beginning of period (in shares)     433,389    
Granted (in shares)     454,320    
Cancelled or forfeited (in shares)     (44,526)    
Outstanding, end of period (in shares) 843,183   843,183   433,389
Vested and Exercisable (in shares) 265,475   265,475    
Weighted-Average Exercise Price          
Outstanding, beginning of period (in dollars per share)     $ 29.05    
Granted (in dollars per share)     4.86    
Cancelled or forfeited (in dollars per share)     32.27    
Outstanding at end of year (in dollars per share) $ 15.85   15.85   $ 29.05
Vested and Exercisable (in dollars per share) $ 35.74   $ 35.74    
Weighted Average Remaining Contractual Term (years)          
Outstanding     8 years 5 months 5 days   7 years 11 months 19 days
Vested and Exercisable     6 years 8 months 16 days    
Aggregate Intrinsic Value          
Outstanding $ 352   $ 352    
Vested and Exercisable $ 4   $ 4    
Stock options          
Stock Incentive Plans          
Vesting period     4 years    
Cliff period for vesting     1 year    
Exercisable period     10 years    
Stock Incentive Plans          
Exercised (in shares) 0 0 0    
Intrinsic value of options exercised       $ 1  
Aggregate fair value of options vested $ 500 $ 300 $ 1,300 $ 1,400  
Weighted average grant date fair value of options granted (in dollars per share) $ 4.10 $ 4.64 $ 3.25 $ 6.64  
Unrecognized compensation expense related to unvested stock option awards $ 2,300   $ 2,300    
Weighted-average amortization period over which cost is expected to be recognized     2 years 3 months 18 days