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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 6,960,253 380,017
Stock options    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 758,304 377,563
Common stock warrants    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 6,201,949 2,454