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Stock Incentive Plans - Plan Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Stock Incentive Plans    
Shares reserved for future issuance (in shares) 7,617,546 5,589,766
Shares    
Outstanding, beginning of period (in shares) 433,389  
Granted (in shares) 454,420  
Cancelled or forfeited (in shares) (101,977)  
Outstanding, end of period (in shares) 785,832 433,389
Vested and Exercisable (in shares) 289,782  
Weighted-Average Exercise Price    
Outstanding, beginning of period (in dollars per share) $ 29.05  
Granted (in dollars per share) 4.86  
Cancelled or forfeited (in dollars per share) 18.12  
Outstanding at end of year (in dollars per share) 16.48 $ 29.05
Vested and Exercisable (in dollars per share) $ 33.91  
Weighted Average Remaining Contractual Term (years)    
Outstanding 8 years 1 month 17 days 7 years 11 months 19 days
Vested and Exercisable 6 years 7 months 2 days  
Aggregate Intrinsic Value    
Outstanding $ 470  
Vested and Exercisable $ 9  
Exercised (in shares) 0  
Stock options    
Stock Incentive Plans    
Vesting period 4 years  
Cliff period for vesting 1 year  
Expiration period 10 years  
Aggregate Intrinsic Value    
Intrinsic value of options exercised   $ 1
Aggregate fair value of options vested $ 1,500 $ 1,700
Weighted average grant date fair value of options granted (in dollars per share) $ 3.25 $ 6.64
Unrecognized compensation expense related to unvested stock option awards $ 1,700  
Weighted-average amortization period over which cost is expected to be recognized 2 years 2 months 12 days