Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Consolidated Statements of Operations
Revenue	$ 0	$ 500
Operating expenses:
Research and development	17,042	18,682
General and administrative	9,329	8,912
Total operating expenses	26,371	27,594
Loss from operations	(26,371)	(27,094)
Other income (expense):
Interest expense	(100)	(462)
Interest and investment income	425	160
Other income, net	176	32
Total other income (expense), net	501	(270)
Net loss	$ (25,870)	$ (27,364)
Net loss per share - basic and diluted (in dollars per share)	$ (5.12)	$ (12.62)
Weighted-average common shares outstanding used in net loss per share - basic and diluted (in shares)	5,054,823	2,168,153