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Property and Equipment (Details) - USD ($)
$ in Thousands
12 Months Ended 24 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2015
Property and Equipment        
Property and equipment, gross $ 1,854 $ 1,466   $ 1,854
Less: accumulated depreciation (1,350) (1,178)   (1,350)
Property and equipment, net 504 288   504
Depreciation and amortization expense 202 248 $ 320  
Lab equipment        
Property and Equipment        
Property and equipment, gross 1,350 1,269   $ 1,350
Estimated Useful Life       3 years
Computer equipment        
Property and Equipment        
Property and equipment, gross 166 110   $ 166
Estimated Useful Life       3 years
Furniture and fixtures        
Property and Equipment        
Property and equipment, gross 77 30   $ 77
Estimated Useful Life       5 years
Leasehold improvements        
Property and Equipment        
Property and equipment, gross $ 261 $ 57   $ 261