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Consolidated Statements of Changes in Stockholders’ (Deficit) Equity - USD ($)
$ in Thousands
Total
Common stock
Additional paid-in capital
Accumulated deficit
Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2020   108,071,249      
Beginning balance at Dec. 31, 2020 $ (18,006) $ 11 $ 391,175 $ (404,629) $ (4,563)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under Employee Stock Purchase Plan (in shares)   34,696      
Issuance of common stock under Employee Stock Purchase Plan 72   72    
Issuance of common stock upon exercise of options (in shares)   153,278      
Issuance of common stock upon exercise of options 244   244    
Issuance of vested restricted stock units (in shares)   10,937      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   4,706,844      
Issuance of common stock through at-the-market offering, net 20,943   20,943    
Stock-based compensation expense 1,780   1,780    
Currency translation adjustment (6)       (6)
Unrealized (losses) on marketable securities (1)       (1)
Net income (loss) (24,597)     (24,597)  
Ending balance (in shares) at Mar. 31, 2021   112,977,004      
Ending balance at Mar. 31, 2021 (19,571) $ 11 414,214 (429,226) (4,570)
Beginning balance (in shares) at Dec. 31, 2020   108,071,249      
Beginning balance at Dec. 31, 2020 (18,006) $ 11 391,175 (404,629) (4,563)
Increase (Decrease) in Stockholders' Equity          
Currency translation adjustment 5        
Unrealized (losses) on marketable securities (1)        
Net income (loss) (37,926)        
Ending balance (in shares) at Sep. 30, 2021   115,443,500      
Ending balance at Sep. 30, 2021 (18,731) $ 12 428,371 (442,555) (4,559)
Beginning balance (in shares) at Mar. 31, 2021   112,977,004      
Beginning balance at Mar. 31, 2021 (19,571) $ 11 414,214 (429,226) (4,570)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock upon exercise of options (in shares)   242,278      
Issuance of common stock upon exercise of options 425   425    
Issuance of vested restricted stock units (in shares)   10,938      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   1,849,072      
Issuance of common stock through at-the-market offering, net 8,563 $ 1 8,562    
Stock-based compensation expense 1,783   1,783    
Currency translation adjustment 12       12
Unrealized (losses) on marketable securities 1       1
Net income (loss) 4,565     4,565  
Ending balance (in shares) at Jun. 30, 2021   115,079,292      
Ending balance at Jun. 30, 2021 (4,222) $ 12 424,984 (424,661) (4,557)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under Employee Stock Purchase Plan (in shares)   24,098      
Issuance of common stock under Employee Stock Purchase Plan 89   89    
Issuance of common stock upon exercise of options (in shares)   1,936      
Issuance of common stock upon exercise of options 5   5    
Issuance of vested restricted stock units (in shares)   10,937      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   327,237      
Issuance of common stock through at-the-market offering, net 1,389   1,389    
Stock-based compensation expense 1,904   1,904    
Currency translation adjustment (1)       (1)
Unrealized (losses) on marketable securities (1)       (1)
Net income (loss) (17,894)     (17,894)  
Ending balance (in shares) at Sep. 30, 2021   115,443,500      
Ending balance at Sep. 30, 2021 $ (18,731) $ 12 428,371 (442,555) (4,559)
Beginning balance (in shares) at Dec. 31, 2021 123,622,965 123,622,965      
Beginning balance at Dec. 31, 2021 $ 22,521 $ 12 457,391 (430,316) (4,566)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under Employee Stock Purchase Plan (in shares)   81,057      
Issuance of common stock under Employee Stock Purchase Plan 127   127    
Issuance of common stock upon exercise of options (in shares)   11,262      
Issuance of common stock upon exercise of options 21   21    
Issuance of vested restricted stock units (in shares)   89,142      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   576,418      
Issuance of common stock through at-the-market offering, net 1,675   1,675    
Other financing fees (79)   (79)    
Stock-based compensation expense 2,753   2,753    
Currency translation adjustment (32)       (32)
Net income (loss) 28,778     28,778  
Ending balance (in shares) at Mar. 31, 2022   124,380,844      
Ending balance at Mar. 31, 2022 $ 55,764 $ 12 461,888 (401,538) (4,598)
Beginning balance (in shares) at Dec. 31, 2021 123,622,965 123,622,965      
Beginning balance at Dec. 31, 2021 $ 22,521 $ 12 457,391 (430,316) (4,566)
Increase (Decrease) in Stockholders' Equity          
Currency translation adjustment 65        
Unrealized (losses) on marketable securities (29)        
Net income (loss) $ 29,486        
Ending balance (in shares) at Sep. 30, 2022 153,028,822 153,028,822      
Ending balance at Sep. 30, 2022 $ 84,907 $ 15 490,252 (400,830) (4,530)
Beginning balance (in shares) at Mar. 31, 2022   124,380,844      
Beginning balance at Mar. 31, 2022 55,764 $ 12 461,888 (401,538) (4,598)
Increase (Decrease) in Stockholders' Equity          
Issuance of vested restricted stock units (in shares)   10,938      
Issuance of vested restricted stock units 0        
Issuance of common stock and common warrants (in shares)   27,428,572      
Issuance of common stock and common warrants 21,480 $ 3 21,477    
Other financing fees 79   79    
Issuance of common stock, license agreement (in shares)   892,857      
Issuance of common stock, license agreement 1,000   1,000    
Stock-based compensation expense 2,564   2,564    
Currency translation adjustment 118       118
Net income (loss) 8,601     8,601  
Ending balance (in shares) at Jun. 30, 2022   152,713,211      
Ending balance at Jun. 30, 2022 89,606 $ 15 487,008 (392,937) (4,480)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under Employee Stock Purchase Plan (in shares)   39,820      
Issuance of common stock under Employee Stock Purchase Plan 62   62    
Issuance of common stock upon exercise of options (in shares)   59,928      
Issuance of common stock upon exercise of options 135   135    
Issuance of vested restricted stock units (in shares)   17,737      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   198,126      
Issuance of common stock through at-the-market offering, net 446   446    
Stock-based compensation expense 2,601   2,601    
Currency translation adjustment (21)       (21)
Unrealized (losses) on marketable securities (29)       (29)
Net income (loss) $ (7,893)     (7,893)  
Ending balance (in shares) at Sep. 30, 2022 153,028,822 153,028,822      
Ending balance at Sep. 30, 2022 $ 84,907 $ 15 $ 490,252 $ (400,830) $ (4,530)