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Income Taxes - Reconciliation of Effective Tax to Statutory Federal Rate (Details)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]      
Tax at federal statutory rate 21.00% 21.00% 35.00%
State taxes, net of federal effect (0.30%) (0.10%) (5.40%)
Foreign rate differential (6.00%) (3.90%) (9.30%)
Tax credits 1.60% 6.30% 4.10%
Domestic production activities deduction 0.00% 0.00% (3.50%)
Stock-based compensation (1.00%) (4.90%) (5.30%)
Change in prior year reserves (1.50%) (0.10%) (2.00%)
Change in valuation allowance (13.40%) (15.20%) (35.20%)
Effect of change in tax rate due to Tax Act 0.00% 0.00% (23.40%)
Other (4.20%) (4.00%) 2.60%
Effective tax rate (3.80%) (0.90%) (42.40%)