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Intangible Assets and Goodwill - Summary of carrying value of intangible assets (Details) - USD ($)
$ in Thousands
Sep. 30, 2017
Dec. 31, 2016
Indefinite-lived Intangible Assets [Line Items]    
Intangible assets $ 99,445 $ 99,445
IPR&D – Immune Modulators    
Indefinite-lived Intangible Assets [Line Items]    
Intangible assets 40,798 40,798
IPR&D – Antigen Inhibitors    
Indefinite-lived Intangible Assets [Line Items]    
Intangible assets 14,811 14,811
IPR&D – cccDNA Sterilizers    
Indefinite-lived Intangible Assets [Line Items]    
Intangible assets $ 43,836 $ 43,836