Income Taxes - Deferred Tax Assets (Details) - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Components of Deferred Tax Assets [Line Items]
Non-capital loss carryforwards	$ 13,932	$ 6,578
Research and development deductions	13,474	14,006
Book amortization in excess of tax	2,142	2,745
Share issue costs	777	1,195
Revenue recognized for tax purposes in excess of revenue recognized for accounting purposes	281	4,086
Tax value in excess of accounting value in lease inducements	77	65
In-process research and development	(146,324)	0
Upfront license fees	629	0
Total deferred tax liabilities	(104,830)
Total deferred tax assets		37,818
Valuation allowance	(41,494)	(37,818)
Net deferred tax liabilities	(146,324)
Net deferred tax assets		0
Federal
Components of Deferred Tax Assets [Line Items]
Investment tax credits	6,303	5,821
Provincial
Components of Deferred Tax Assets [Line Items]
Investment tax credits	$ 3,879	$ 3,322