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Interim Financial Data (Unaudited) (Tables)
12 Months Ended
Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract]  
Schedule of interim financial data (unaudited)
 
2015
 
Q1

 
Q2

 
Q3

 
Q4

 
Total

Revenue
$
4,682

 
$
3,440

 
$
4,065

 
$
12,686

 
$
24,873

Loss from operations
(18,006
)
 
(14,420
)
 
(58,138
)
 
(11,758
)
 
(102,322
)
Net loss
$
(11,989
)
 
$
(14,886
)
 
$
(28,982
)
 
$
(5,264
)
 
$
(61,121
)
Basic and diluted net loss per share
$
(0.40
)
 
$
(0.27
)
 
$
(0.57
)
 
$
(0.10
)
 
$
(1.34
)
 
2014
 
Q1

 
Q2

 
Q3

 
Q4

 
Total

Revenue
$
4,430

 
$
1,811

 
$
4,362

 
$
4,350

 
$
14,953

Loss from operations
(5,958
)
 
(9,423
)
 
(6,844
)
 
(10,747
)
 
(33,434
)
Net loss
$
(17,984
)
 
$
(6,081
)
 
$
(8,604
)
 
$
(6,168
)
 
$
(38,837
)
Basic and diluted net loss per share
$
(0.91
)
 
$
(0.28
)
 
$
(0.39
)
 
$
(0.27
)
 
$
(1.80
)