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Shareholders’ equity - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Oct. 02, 2017
Sep. 30, 2022
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Sep. 30, 2022
Mar. 03, 2022
Nov. 04, 2021
Oct. 18, 2021
Oct. 08, 2021
Mar. 04, 2021
Oct. 22, 2020
Aug. 07, 2020
Jan. 10, 2020
Class of Stock [Line Items]                            
Issuance of common shares pursuant to the agreement   $ 8,973 $ 44,736 $ 4,274 $ 26,419                  
Number of common shares issued upon conversion of preferred shares                 22,833,922          
Preferred stock, shares authorized (in shares)   1,164,000       1,164,000                
Common Shares | Jan 2020 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement                           $ 150,000
Common Shares | Oct 2020 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement                       $ 200,000    
Common Shares | Nov 2021 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement               $ 250,000            
Jefferies LLC | Common Shares                            
Class of Stock [Line Items]                            
Number of shares issued under agreement (in sales)     19,715,142     3,901,765                
Jefferies LLC | Common Shares | Sale Agreement [Member]                            
Class of Stock [Line Items]                            
Proceeds from issuance of shares under the agreement     $ 75,400     $ 9,200                
Jefferies LLC | Common Shares | Mar 2021 Prospectus Supplement Agreement [Member] | Oct 2020 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement                     $ 75,000      
Jefferies LLC | Common Shares | October 2021 Prospectus Supplement                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement   $ 142,600       142,600                
Jefferies LLC | Common Shares | October 2021 Prospectus Supplement | Oct 2020 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement                   $ 75,000        
Jefferies LLC | Common Shares | March 2022 Prospectus Supplement [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement   $ 142,600       $ 142,600                
Jefferies LLC | Common Shares | March 2022 Prospectus Supplement [Member] | Jan 2020 Oct 2020 and Nov 2021 Registration Stmts                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement             $ 100,000              
Jefferies LLC | Common Shares | Jan 2020 Prospectus Supplement | Jan 2020 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement                           $ 50,000
Jefferies LLC | Common Shares | Aug 2020 Prospectus Supplement | Jan 2020 Registration Stmt [Member]                            
Class of Stock [Line Items]                            
Aggregate sale price of common shares under agreement                         $ 75,000  
Roivant Sciences Ltd                            
Class of Stock [Line Items]                            
Ownership percentage by noncontrolling owners after conversion   25.00%       25.00%                
Roivant Sciences Ltd | Convertible Preferred Stock                            
Class of Stock [Line Items]                            
Issuance of common shares pursuant to the agreement $ 116,400                          
Preferred stated value (in USD per share) $ 7.13                          
Premium on closing stock price (as a percent) 15.00%                          
Share price (in USD per share) $ 6.20                          
Preferred stock dividend rate as a percent 8.75%         8.75%