Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 78,872	$ 36,942
Short-term investments	16,410	87,675
Accounts receivable	1,531	1,431
Prepaid expenses and other current assets	2,770	3,181
Total current assets	99,583	129,229
Investment in Genevant	14,377	22,224
Property and equipment, net of accumulated depreciation $8,105 (2018-$7,090)	9,402	10,145
Right of use asset (note 8)	2,901	0
Intangible assets	43,836	43,836
Goodwill	22,471	22,471
Total assets	192,570	227,905
Current liabilities:
Accounts payable and accrued liabilities	7,940	9,429
Site consolidation accrual	342	1,331
Liability-classified options	141	479
Lease liability, current	376	0
Total current liabilities	8,799	11,239
Deferred rent and inducements, non-current	0	645
Contingent consideration	3,381	3,126
Lease liability, non-current	3,263	0
Deferred tax liability	12,661	12,661
Total liabilities	28,104	27,671
Stockholders’ equity:
Preferred shares, Authorized - 1,164,000 with no par value, Issued and outstanding: 1,164,000 (December 31, 2018 - 1,164,000)	131,613	126,136
Common shares, Authorized - unlimited number with no par value, Issued and outstanding: 56,850,172 (December 31, 2018 - 55,518,800)	884,623	879,405
Additional paid-in capital	53,738	48,084
Deficit	(857,264)	(805,221)
Accumulated other comprehensive loss	(48,244)	(48,170)
Total stockholders' equity	164,466	200,234
Total liabilities and stockholders' equity	$ 192,570	$ 227,905