Consolidated Statement of Stockholders’ Equity - USD ($) $ in Thousands	Total	Convertible Preferred Shares	Common Shares	Additional paid-in capital	Deficit	Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2016		0	54,841,494
Beginning balance at Dec. 31, 2016	$ 203,005	$ 0	$ 867,393	$ 36,543	$ (652,746)	$ (48,185)
Issuance of Preferred Shares, net of issuance cost (in shares)		500,000
Issuance of Preferred Shares, net of issuance cost	48,869	$ 48,869
Accrual of coupon on Preferred Shares	0	$ 911			(911)
Stock-based compensation	14,858		$ 7,972	6,886
Certain fair value adjustments to liability stock option awards	(540)			(540)
Issuance of common shares pursuant to exercise of options (in shares)			40,156
Issuance of common shares pursuant to exercise of options	213		$ 262	(49)
Issuance of common shares pursuant to exercise of warrants (in shares)			179,000
Issuance of common shares pursuant to exercise of warrants	481		$ 481
Net loss	(84,413)				(84,413)
Ending balance (in shares) at Dec. 31, 2017		500,000	55,060,650
Ending balance at Dec. 31, 2017	182,473	$ 49,780	$ 876,108	42,840	(738,070)	(48,185)
Issuance of Preferred Shares, net of issuance cost (in shares)		664,000
Issuance of Preferred Shares, net of issuance cost	66,265	$ 66,265
Accrual of coupon on Preferred Shares	0	$ 10,091			(10,091)
Stock-based compensation	6,687			6,687
Certain fair value adjustments to liability stock option awards	472			472
Issuance of common shares pursuant to exercise of options (in shares)			458,150
Issuance of common shares pursuant to exercise of options	1,382		$ 3,297	(1,915)
Currency translation adjustment	15					15
Net loss	(57,060)				(57,060)
Ending balance (in shares) at Dec. 31, 2018		1,164,000	55,518,800
Ending balance at Dec. 31, 2018	$ 200,234	$ 126,136	$ 879,405	$ 48,084	$ (805,221)	$ (48,170)