Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 504,365	$ 620,129
Accounts receivable, net	102,357	114,042
Prepaid expenses and other current assets	9,854	8,689
Restricted cash	1,250	1,250
Convertible note hedges		1,115
Total current assets	617,826	745,225
Restricted cash, net of current portion	485	485
Accounts receivable, net of current portion	14,289	23,998
Property and equipment, net	6,964	7,575
Operating lease right-of-use assets	14,700	15,350
Deferred tax assets	320,554	333,294
Other assets	872	1,000
Total assets	975,690	1,126,927
Current liabilities:
Accounts payable	317	935
Accrued research and development costs	6,338	15,896
Accrued expenses and other current liabilities	13,425	23,566
Current portion of operating lease liabilities	3,066	3,127
Current portion of convertible senior notes		116,858
Note hedge warrants	152	1,316
Total current liabilities	23,298	161,698
Convertible senior notes, net of current portion	395,451	337,333
Operating lease obligations, net of current portion	17,567	18,484
Other liabilities	6,491	3,501
Commitments and contingencies
Stockholders' equity:
Class A Common Stock, $0.001 par value, 500,000,000 shares authorized and 153,176,309 shares issued and outstanding at June 30, 2022 and 500,000,000 shares authorized and 162,036,461 shares issued and outstanding at December 31, 2021	153	162
Additional paid-in capital	1,328,290	1,543,357
Accumulated deficit	(795,560)	(937,608)
Total stockholders' equity	532,883	605,911
Total liabilities and stockholders' equity	$ 975,690	$ 1,126,927