Collaboration, License, Promotion and Other Commercial Agreements - North America - Commercial Efforts (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Collaboration, License, Promotion and Other Commercial Agreements
Revenue	$ 103,747	$ 103,468	$ 296,623	$ 272,843
Selling, general and administrative costs incurred by the Company	27,742	34,928	82,446	106,021
AbbVie | U.S.
Collaboration, License, Promotion and Other Commercial Agreements
Patent litigation costs			200	400
Collaborative arrangements revenue
Collaboration, License, Promotion and Other Commercial Agreements
Revenue	103,747	103,468	295,798	267,336
Collaborative arrangements, LINZESS | AbbVie | U.S.
Collaboration, License, Promotion and Other Commercial Agreements
Selling, general and administrative costs incurred by the Company	$ 7,400	$ 6,200	$ 22,000	$ 19,200