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Note 16 - Subsequent Events (Details Textual) - Equity Line Purchase Agreement [Member] - USD ($)
3 Months Ended 12 Months Ended
Oct. 24, 2019
Mar. 28, 2022
Dec. 31, 2021
Dec. 31, 2020
Stock Issued During Period, Shares, New Issues (in shares) 104,651   647,504 4,231,073
Stock Issued During Period, Value, New Issues $ 450,000   $ 675,590 $ 4,891,348
Subsequent Event [Member]        
Stock Issued During Period, Shares, New Issues (in shares)   120,000    
Stock Issued During Period, Value, New Issues   $ 86,885