Note 9 - Loss Per Share - Shares Used in Basic and Diluted Loss Per Common Share Computations (Details) - USD ($)		12 Months Ended
		Dec. 31, 2020	Dec. 31, 2019
Net loss attributable to common shareholders per common share: basic and diluted calculation		$ (26,438,684)	$ (19,680,701)
Weighted average common shares outstanding-basic (in shares)		11,950,154	2,870,132
Effect of diluted stock options, warrants and preferred stock (1) (in shares)	[1]
Weighted average common shares outstanding-diluted (in shares)		11,950,154	2,870,132
Loss per common share-basic and diluted (in dollars per share)		$ 2.21	$ 6.86

[1] The following is a summary of the number of underlying shares outstanding at the end of the respective periods that have been excluded from the diluted calculations because the effect on loss per common share would have been anti-dilutive: Year Ended December 31, 2020 2019 Options 1,013,547 766,424 Warrants 7,353,376 2,171,610 Convertible debt 1,107,544 82,751 Preferred stock: Series B 7,925 7,925 Preferred stock: Series D - 350,00- Preferred stock: Series E - 594,383