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Note 1 - Summary of Significant Accounting Policies (Details Textual)
1 Months Ended 2 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Mar. 01, 2021
USD ($)
Oct. 29, 2019
Oct. 28, 2019
Oct. 24, 2019
USD ($)
shares
Feb. 23, 2021
USD ($)
shares
Oct. 31, 2019
USD ($)
Feb. 28, 2021
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Dec. 31, 2020
USD ($)
shares
Dec. 31, 2019
USD ($)
shares
Apr. 04, 2019
Jan. 01, 2019
USD ($)
Mar. 31, 2018
Retained Earnings (Accumulated Deficit), Ending Balance               $ (108,383,108)   $ (108,383,108) $ (82,498,711)      
Repayments of Debt                   1,472,389 1,154,513      
Operating Lease, Right-of-Use Asset               1,395,351   1,395,351 729,745      
Operating Lease, Liability, Current               597,469   597,469 459,481      
Accounts Receivable, Allowance for Credit Loss, Current               0   0 0      
Impairment of Intangible Assets (Excluding Goodwill), Total                   0 770,250      
Goodwill, Impairment Loss               9,879,458 $ 2,997,000 12,876,498 8,100,000      
Accounts Receivable, after Allowance for Credit Loss, Total               256,878   256,878 297,055      
Contract with Customer, Liability, Total               53,028   53,028 40,384      
Research and Development Expense, Total                   372,710 422,964      
Income Tax Expense (Benefit), Total                   0      
Unrecognized Tax Benefits, Ending Balance               0   0        
Cash, Uninsured Amount               238,504   238,504        
Licensing Agreements [Member]                            
Impairment of Intangible Assets (Excluding Goodwill), Total                   $ 0 $ 770,250      
Accounting Standards Update 2016-02 [Member]                            
Operating Lease, Right-of-Use Asset                         $ 353,007  
Operating Lease, Liability, Current                         $ 79,252  
Subsequent Event [Member]                            
Stock Issued During Period, Shares, New Issues (in shares) | shares         22,536,864                  
Proceeds from Issuance or Sale of Equity, Net of Stock Issuance Costs         $ 31,077,232   $ 31,077,232              
Subsequent Event [Member] | Debt Issued in September 2018, September, 2019, and February 2020 [Member]                            
Repayments of Debt $ 5,906,802                          
Equity Line Purchase Agreement [Member]                            
Issuance or Sale of Equity, Can Be Raised       $ 15,000,000                    
Stock Issued During Period, Shares, New Issues (in shares) | shares       104,651           4,231,073 122,356      
Stock Issued During Period, Value, New Issues       $ 450,000           $ 4,891,348 $ 319,196      
Sale of Stock, Remaining Available Balance               9,789,419   $ 9,789,419        
Equity Line Purchase Agreement [Member] | Investor [Member]                            
Issuance or Sale of Equity, Can Be Raised           $ 15,000,000                
Sale of Equity, Term (Year)           3 years                
Stock Issued During Period, Shares, New Issues (in shares) | shares                   4,353,429        
Stock Issued During Period, Value, New Issues                   $ 5,210,581        
Sale of Stock, Remaining Available Balance               $ 9,789,419   $ 9,789,419        
Helomics Holding Corp. [Member]                            
Business Combination, Step Acquisition, Equity Interest in Acquiree, Percentage                           25.00%
Business Acquisition, Percentage of Voting Interests Acquired                       75.00%    
Reverse Stock Split [Member]                            
Stockholders' Equity Note, Stock Split, Conversion Ratio   0.1 10