Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	Merger [Member]	Preferred Units [Member]	Common Units [Member]	Common Stock [Member]	Common Stock [Member] Merger [Member]	Additional Paid-in Capital [Member]	Additional Paid-in Capital [Member] Merger [Member]	Accumulated Deficit [Member]	Yumanity Holdings LLC [Member]	Yumanity Holdings LLC [Member] Preferred Units [Member]	Yumanity Holdings LLC [Member] Common Units [Member]	Yumanity Holdings LLC [Member] Defaulting Class B Preferred Units [Member]	Yumanity Holdings LLC [Member] Common Stock [Member]	Yumanity Holdings LLC [Member] Additional Paid-in Capital [Member]	Class C Preferred Units [Member] Preferred Units [Member]	Class B Preferred Units [Member]	Class B Preferred Units [Member] Preferred Units [Member]	Class B Preferred Units [Member] Defaulting Class B Preferred Units [Member]	Class B Preferred Units [Member] Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2019	$ (91,900)		$ 89,699	$ 5,120					$ (97,020)
Beginning balance, shares at Dec. 31, 2019			12,391,101	2,163,099
Forfeiture of unvested incentive units, shares				(790)
Stock/equity-based compensation expense	2,266			$ 2,266
Gain on extinguishment of Ordinary Class B preferred units																	$ 6,697	$ (6,697)		$ 6,697
Exchange of common stock in connection with the Merger		$ 60,130				$ 3		$ 60,127
Exchange of common stock in connection with the Merger, shares						2,708,537
Fair value of replacement equity	471						$ 471
Reclassification of warrant liability to permanent equity	189						189
Issuance of common stock, net of issuance costs																$ 21,235
Issuance of common stock, net of issuance costs, shares																5,404,588
Exchange of Units, Value										$ 103,949				$ 4	$ 104,233
Exchange of Units, Number														3,745,983
Exchange of Units, Value											$ (103,949)		$ (288)
Exchange of Units, Number											(16,959,370)		(836,319)
Exchange of Units, Number												(2,162,309)		2,278,450				(836,319)	836,319
Exchange of Units, Value												$ (7,386)		$ 2	$ 7,384		288	$ (288)	$ 288
Private placement of common stock, net of issuance costs of $1,996	31,604				$ 1		31,603
Private placement of common stock, net of issuance costs of $1,996, shares					1,460,861
Net loss	(57,487)								(57,487)
Ending balance at Dec. 31, 2020	56,207				$ 10		204,007		(147,810)
Ending balance, shares at Dec. 31, 2020					10,193,831
Stock/equity-based compensation expense	$ 5,290						5,290
Exercises of common stock options, shares	9,241				9,241
Exercises of common stock options	$ 84						84
Vesting of restricted stock unit, shares					23,146
Issuance of restricted stock awards					$ 1		(1)
Issuance of restricted stock awards, shares					305,663
Gain on extinguishment of Ordinary Class B preferred units																	$ 0
Issuance of common stock, net of issuance costs	1,419						1,419
Issuance of common stock, net of issuance costs, shares					112,833
Net loss	(39,503)								(39,503)
Ending balance at Dec. 31, 2021	$ 23,497				$ 11		$ 210,799		$ (187,313)
Ending balance, shares at Dec. 31, 2021					10,644,714