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Income Taxes - Income Tax Expense by Applying Statutory Federal Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]      
Tax at statutory federal rate 21.00% 21.00% 21.00%
State tax, net of federal benefit (0.20%) (0.10%) (0.40%)
Foreign rate differential (0.40%) (0.70%) (1.00%)
Tax credits 1.40% 3.00% 2.80%
Stock-based compensation 9.80% 3.80% 2.00%
Change in valuation allowance (33.60%) (26.40%) (21.20%)
Other 0.90% (2.20%) (4.90%)
Total (1.10%) (1.60%) (1.70%)