Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023
Cash flows from operating activities
Net loss	$ (55,075)	$ (152,126)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,228	1,070
Net amortization of premiums and discounts on marketable securities	(3,335)	(4,239)
Stock-based compensation	13,112	17,051
Non-cash operating lease expense	2,302	2,051
Other non-cash items	230	536
Changes in operating assets and liabilities:
Accounts receivable	(1,000)	30,000
Prepaid expenses and other current assets	585	(244)
Other assets	(500)	0
Accounts payable	(5,154)	(659)
Accrued expenses	(3,271)	(13,617)
Operating lease liabilities	(2,353)	(2,186)
Other liabilities	418	0
Deferred revenue	(10,276)	(14,557)
Net cash used in operating activities	(63,089)	(136,920)
Cash flows from investing activities
Maturities of marketable securities	95,000	232,970
Purchase of marketable securities	(133,431)	(131,453)
Purchase of property and equipment	(132)	(1,782)
Net cash (used in) provided by investing activities	(38,563)	99,735
Cash flows from financing activities
Net proceeds from at-the-market facilities	5,780	93,539
Proceeds from exercise of stock options	56	427
Proceeds from sales of common stock pursuant to ESPP	258	963
Payment of debt issuance costs	0	(150)
Payments under finance lease obligations	(135)	(196)
Net cash provided by financing activities	5,959	94,583
(Decrease) increase in cash, cash equivalents and restricted cash	(95,693)	57,398
Cash, cash equivalents and restricted cash, beginning of period	175,039	129,363
Cash, cash equivalents and restricted cash, end of period	79,346	186,761
Supplemental cash flow information:
Purchases of property and equipment in accounts payable and accrued expenses	0	442
Cash paid for interest	$ 2,630	$ 2,508