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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
At market equity offering programs
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Balance at beginning of period (in shares) at Dec. 31, 2020     68,841,288      
Balance at beginning of period at Dec. 31, 2020 $ 228,087   $ 7 $ 508,499 $ 0 $ (280,419)
Increase (Decrease) in Stockholders' Equity            
Exercise of stock options (in shares)     148,472      
Exercise of stock options 764     764    
Vesting of restricted stock units, net of employee tax obligations (in shares)     61,678      
Vesting of restricted stock units, net of employee tax obligations (259)     (259)    
Stock-based compensation expense 4,039     4,039    
Net (loss) income (34,693)         (34,693)
Balance at end of period (in shares) at Mar. 31, 2021     69,051,438      
Balance at end of period at Mar. 31, 2021 197,938   $ 7 513,043 0 (315,112)
Balance at beginning of period (in shares) at Dec. 31, 2020     68,841,288      
Balance at beginning of period at Dec. 31, 2020 228,087   $ 7 508,499 0 (280,419)
Increase (Decrease) in Stockholders' Equity            
Net (loss) income (121,077)          
Balance at end of period (in shares) at Sep. 30, 2021     71,865,399      
Balance at end of period at Sep. 30, 2021 155,549   $ 7 557,038 0 (401,496)
Balance at beginning of period (in shares) at Mar. 31, 2021     69,051,438      
Balance at beginning of period at Mar. 31, 2021 197,938   $ 7 513,043 0 (315,112)
Increase (Decrease) in Stockholders' Equity            
Issuance of common stock under public offering, net of issuance costs (in shares)     2,271,074      
Issuance of common stock under public offering, net of issuance costs 33,287     33,287    
Exercise of stock options (in shares)     42,506      
Exercise of stock options 202     202    
Purchase of common stock under ESPP (in shares)     36,198      
Purchase of common stock under ESPP 417     417    
Stock-based compensation expense 4,582     4,582    
Net (loss) income (40,913)         (40,913)
Balance at end of period (in shares) at Jun. 30, 2021     71,401,216      
Balance at end of period at Jun. 30, 2021 195,513   $ 7 551,531 0 (356,025)
Increase (Decrease) in Stockholders' Equity            
Stock issuance costs   $ 746        
Exercise of stock options (in shares)     137,301      
Exercise of stock options 579     579    
Vesting of restricted stock units, net of employee tax obligations (in shares)     326,882      
Stock-based compensation expense 4,928     4,928    
Net (loss) income (45,471)         (45,471)
Balance at end of period (in shares) at Sep. 30, 2021     71,865,399      
Balance at end of period at Sep. 30, 2021 155,549   $ 7 557,038 0 (401,496)
Balance at beginning of period (in shares) at Dec. 31, 2021     73,709,056      
Balance at beginning of period at Dec. 31, 2021 121,741   $ 7 572,213   (450,479)
Increase (Decrease) in Stockholders' Equity            
Issuance of common stock under public offering, net of issuance costs (in shares)     13,169,903      
Issuance of common stock under public offering, net of issuance costs 60,462   $ 2 60,460    
Exercise of stock options (in shares)     26,951      
Exercise of stock options 96     96    
Vesting of restricted stock units, net of employee tax obligations (in shares)     167,174      
Stock-based compensation expense 5,485     5,485    
Net (loss) income (47,258)         (47,258)
Balance at end of period (in shares) at Mar. 31, 2022     87,073,084      
Balance at end of period at Mar. 31, 2022 140,526   $ 9 638,254   (497,737)
Increase (Decrease) in Stockholders' Equity            
Stock issuance costs   1,322        
Balance at beginning of period (in shares) at Dec. 31, 2021     73,709,056      
Balance at beginning of period at Dec. 31, 2021 $ 121,741   $ 7 572,213   (450,479)
Increase (Decrease) in Stockholders' Equity            
Exercise of common stock warrant in exchange for common stock (in shares)     16,654      
Exercise of stock options (in shares) 54,299          
Net (loss) income $ (159,288)          
Balance at end of period (in shares) at Sep. 30, 2022     98,582,583      
Balance at end of period at Sep. 30, 2022 90,229   $ 10 700,217 (231) (609,767)
Balance at beginning of period (in shares) at Mar. 31, 2022     87,073,084      
Balance at beginning of period at Mar. 31, 2022 140,526   $ 9 638,254   (497,737)
Increase (Decrease) in Stockholders' Equity            
Issuance of common stock under public offering, net of issuance costs (in shares)     9,904,964      
Issuance of common stock under public offering, net of issuance costs 39,899   $ 1 39,898    
Exercise of common stock warrant in exchange for common stock (in shares)     16,654      
Purchase of common stock under ESPP (in shares)     154,235      
Purchase of common stock under ESPP 606     606    
Vesting of restricted stock units, net of employee tax obligations (in shares)     17,417      
Stock-based compensation expense 5,348     5,348    
Other comprehensive income (loss), net of tax, portion attributable to parent (126)       (126)  
Net (loss) income (52,219)         (52,219)
Balance at end of period (in shares) at Jun. 30, 2022     97,166,354      
Balance at end of period at Jun. 30, 2022 134,034   $ 10 684,106 (126) (549,956)
Increase (Decrease) in Stockholders' Equity            
Stock issuance costs   941        
Issuance of common stock under public offering, net of issuance costs (in shares)     1,382,631      
Issuance of common stock under public offering, net of issuance costs 10,626     10,626    
Exercise of stock options (in shares)     27,348      
Exercise of stock options 110     110    
Vesting of restricted stock units, net of employee tax obligations (in shares)     6,250      
Stock-based compensation expense 5,375     5,375    
Other comprehensive income (loss), net of tax, portion attributable to parent (105)       (105)  
Net (loss) income (59,811)         (59,811)
Balance at end of period (in shares) at Sep. 30, 2022     98,582,583      
Balance at end of period at Sep. 30, 2022 $ 90,229   $ 10 $ 700,217 $ (231) $ (609,767)
Increase (Decrease) in Stockholders' Equity            
Stock issuance costs   $ 251