0001104659-24-061155.txt : 20240514 0001104659-24-061155.hdr.sgml : 20240514 20240514161209 ACCESSION NUMBER: 0001104659-24-061155 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20240331 FILED AS OF DATE: 20240514 DATE AS OF CHANGE: 20240514 EFFECTIVENESS DATE: 20240514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: PFM Health Sciences, LP CENTRAL INDEX KEY: 0001442756 ORGANIZATION NAME: IRS NUMBER: 262000428 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13169 FILM NUMBER: 24944470 BUSINESS ADDRESS: STREET 1: 475 SANSOME STREET STREET 2: SUITE 1720 CITY: SAN FRANCISCO STATE: CA ZIP: 94111 BUSINESS PHONE: 415-281-1022 MAIL ADDRESS: STREET 1: 475 SANSOME STREET STREET 2: SUITE 1720 CITY: SAN FRANCISCO STATE: CA ZIP: 94111 FORMER COMPANY: FORMER CONFORMED NAME: Partner Fund Management, L.P. DATE OF NAME CHANGE: 20080812 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001442756 XXXXXXXX 03-31-2024 03-31-2024 false PFM Health Sciences, LP

475 Sansome Street Suite 1720 San Francisco CA 94111

13F HOLDINGS REPORT 028-13169 N Darren Mooney 415-281-1000 /s/ Darren Mooney San Francisco CA 05-08-2024 0 87 2127260197 INFORMATION TABLE 2 infotable.xml ABBVIE INC COM 00287Y109 73543088 403861 SH DFND 0 403861 0 ACADIA HEALTHCARE COMPANY IN COM 00404A109 21209887 267734 SH DFND 0 267734 0 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 16468553 10423135 SH DFND 0 10423135 0 ALIGN TECHNOLOGY INC COM 016255101 7460508 22751 SH DFND 0 22751 0 ALKERMES PLC SHS G01767105 11628541 429573 SH DFND 0 429573 0 APELLIS PHARMACEUTICALS INC COM 03753U106 4875919 82952 SH DFND 0 82952 0 ARCELLX INC COMMON STOCK 03940C100 21088256 303210 SH DFND 0 303210 0 ARGENX SE SPONSORED ADR 04016X101 34187495 86832 SH DFND 0 86832 0 ARK ETF TR INNOVATION ETF 00214Q104 12132381 242260 SH DFND 0 242260 0 ASCENDIS PHARMA A/S NOTE 2.250% 4/0 04351PAD3 6933239 6000000 PRN DFND 0 6000000 0 ASTRIA THERAPEUTICS INC COM 04635X102 4603158 327045 SH DFND 0 327045 0 AVANTOR INC COM 05352A100 34348411 1343309 SH DFND 0 1343309 0 AXSOME THERAPEUTICS INC COM 05464T104 37300675 467427 SH DFND 0 467427 0 BECTON DICKINSON & CO COM 075887109 42450542 171552 SH DFND 0 171552 0 BIOMARIN PHARMACEUTICAL INC NOTE 0.599% 8/0 09061GAH4 14766000 15000000 PRN DFND 0 15000000 0 BLUEBIRD BIO INC COM 09609G100 2614593 2042651 SH DFND 0 2042651 0 BOSTON SCIENTIFIC CORP COM 101137107 11834113 172786 SH DFND 0 172786 0 BOUNDLESS BIO INC COM 10170A100 2002310 140513 SH DFND 0 140513 0 CARIBOU BIOSCIENCES INC COM 142038108 33324008 6483270 SH DFND 0 6483270 0 CELCUITY INC COM 15102K100 10735243 497002 SH DFND 0 497002 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 1468950 35000 SH DFND 0 35000 0 CENTENE CORP DEL COM 15135B101 46971300 598513 SH DFND 0 598513 0 CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 3555816 314674 SH DFND 0 314674 0 COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 9065405 1089592 SH DFND 0 1089592 0 CULLINAN ONCOLOGY INC COM 230031106 4361678 255967 SH DFND 0 255967 0 CYTOKINETICS INC COM NEW 23282W605 123196731 1757192 SH DFND 0 1757192 0 CYTOKINETICS INC NOTE 3.500% 7/0 23282WAC4 11448000 7200000 PRN DFND 0 7200000 0 DANAHER CORPORATION COM 235851102 31343606 125515 SH DFND 0 125515 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 5868747 355251 SH DFND 0 355251 0 DEXCOM INC COM 252131107 21620279 155878 SH DFND 0 155878 0 EDWARDS LIFESCIENCES CORP COM 28176E108 70739246 740260 SH DFND 0 740260 0 ELEVANCE HEALTH INC COM 036752103 28649335 55250 SH DFND 0 55250 0 ELI LILLY & CO COM 532457108 232332308 298643 SH DFND 0 298643 0 ERASCA INC COM 29479A108 5222310 2535102 SH DFND 0 2535102 0 ESSA PHARMA INC COM NEW 29668H708 25303766 2980420 SH DFND 0 2980420 0 EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 3531904 170871 SH DFND 0 170871 0 GENERATION BIO CO COM 37148K100 6603522 1622487 SH DFND 0 1622487 0 HCA HEALTHCARE INC COM 40412C101 23947454 71800 SH Call DFND 0 71800 0 HCA HEALTHCARE INC COM 40412C101 41637885 124840 SH DFND 0 124840 0 HUMANA INC COM 444859102 43457885 125340 SH DFND 0 125340 0 ICON PLC SHS G4705A100 38878150 115726 SH DFND 0 115726 0 IMMUNOVANT INC COM 45258J102 15267767 472540 SH DFND 0 472540 0 INHIBRX INC COM 45720L107 1675213 47918 SH DFND 0 47918 0 INSPIRE MED SYS INC COM 457730109 7207708 33557 SH DFND 0 33557 0 INTRA-CELLULAR THERAPIES INC COM 46116X101 6842427 98879 SH DFND 0 98879 0 INTUITIVE SURGICAL INC COM NEW 46120E602 44313756 111037 SH DFND 0 111037 0 IO BIOTECH INC COM 449778109 4050115 2341107 SH DFND 0 2341107 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 4605374 310754 SH DFND 0 310754 0 IQVIA HLDGS INC COM 46266C105 28286758 111854 SH DFND 0 111854 0 ISHARES TR CHINA LG-CAP ETF 464287184 3396807 141122 SH DFND 0 141122 0 ISHARES TR RUSSELL 2000 ETF 464287655 20843885 99115 SH DFND 0 99115 0 ISHARES TR 2 CHINA LG-CAP ETF 464287184 24618796 1022800 SH Call DFND 0 1022800 0 ISHARES TR 3 RUSSELL 2000 ETF 464287655 18632580 88600 SH Call DFND 0 88600 0 ISHARES TR 4 20 YR TR BD ETF 464287432 49486260 523000 SH Put DFND 0 523000 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 41186494 734293 SH DFND 0 734293 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 8003990 29973 SH DFND 0 29973 0 MCKESSON CORP COM 58155Q103 52341801 97498 SH DFND 0 97498 0 MERCK & CO INC COM 58933Y105 78676639 596261 SH DFND 0 596261 0 METAGENOMI INC COM 59102M104 13366871 1267002 SH DFND 0 1267002 0 MOLINA HEALTHCARE INC COM 60855R100 28794253 70088 SH DFND 0 70088 0 NEVRO CORP NOTE 2.750% 4/0 64157FAC7 16581250 17500000 PRN DFND 0 17500000 0 OSCAR HEALTH INC CL A 687793109 12800408 860821 SH DFND 0 860821 0 OUTSET MED INC COM 690145107 2593038 1168035 SH DFND 0 1168035 0 PENUMBRA INC COM 70975L107 34768319 155786 SH DFND 0 155786 0 PMV PHARMACEUTICALS INC COM 69353Y103 2168285 1275462 SH DFND 0 1275462 0 PRAXIS PRECISION MEDICINES I COM NEW 74006W207 29143457 477605 SH DFND 0 477605 0 SAGIMET BIOSCIENCES INC COM SER A 786700104 4350699 802712 SH DFND 0 802712 0 SANA BIOTECHNOLOGY INC COM 799566104 6750000 675000 SH DFND 0 675000 0 SAREPTA THERAPEUTICS INC COM 803607100 1461733 11291 SH DFND 0 11291 0 SILK RD MED INC COM 82710M100 6065092 331064 SH DFND 0 331064 0 STRYKER CORPORATION COM 863667101 19715774 55092 SH DFND 0 55092 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 15676917 658694 SH DFND 0 658694 0 TENAYA THERAPEUTICS INC COM 87990A106 1162221 222222 SH DFND 0 222222 0 TENET HEALTHCARE CORP COM NEW 88033G407 61952780 589409 SH DFND 0 589409 0 THERMO FISHER SCIENTIFIC INC COM 883556102 33732266 58038 SH DFND 0 58038 0 TURNSTONE BIOLOGICS CORP COM 90042W100 2412957 920976 SH DFND 0 920976 0 UNIQURE NV SHS N90064101 1427608 274540 SH DFND 0 274540 0 UNITEDHEALTH GROUP INC COM 91324P102 9577887 19361 SH DFND 0 19361 0 UNIVERSAL HLTH SVCS INC CL B 913903100 39043338 213983 SH DFND 0 213983 0 VEEVA SYS INC CL A COM 922475108 27549099 118905 SH DFND 0 118905 0 VERTEX PHARMACEUTICALS INC COM 92532F100 62221625 148852 SH DFND 0 148852 0 VIKING THERAPEUTICS INC COM 92686J106 2691814 32827 SH DFND 0 32827 0 WATERS CORP COM 941848103 13240463 38464 SH DFND 0 38464 0 WEREWOLF THERAPEUTICS INC COM 95075A107 19483636 3006734 SH DFND 0 3006734 0 WEST PHARMACEUTICAL SVSC INC COM 955306105 20259165 51197 SH DFND 0 51197 0 XENON PHARMACEUTICALS INC COM 98420N105 6481350 150554 SH DFND 0 150554 0 ZIMMER BIOMET HOLDINGS INC COM 98956P102 39640325 300351 SH DFND 0 300351 0