The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AFFIMED N V COM N01045108 2,445 287,600 SH   SOLE   2,445 0 0
AFFIRM HLDGS INC COM CL A 00827B106 337 5,000 SH   SOLE   337 0 0
AIRBNB INC COM CL A 009066101 8 50 SH   SOLE   8 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 17 1,500 SH   SOLE   17 0 0
AMAZON.COM INC COM 023135106 689 200 SH   SOLE   689 0 0
AMPIO PHARMACEUTICALS INC COM 03209T109 487 291,500 SH   SOLE   487 0 0
ANNOVIS BIO INC COM COM 03615A108 1,027 12,000 SH   SOLE   1,027 0 0
APPLIED GENETIC TECHNOLOGIES COM 03820J100 79 20,000 SH   SOLE   79 0 0
APPLIED THERAPEUTICS INC COM 03828A101 780 37,500 SH   SOLE   780 0 0
ARAVIVE INC COM 03890D108 141 23,500 SH   SOLE   141 0 0
ARCTURUS THERAPEUTICS HLDGS COM 03969T109 15,408 455,300 SH   SOLE   15,408 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 328 12,000 SH   SOLE   328 0 0
ARROWHEAD PHARMACEUTICALS INC COM 04280A100 17,277 208,600 SH   SOLE   17,277 0 0
ASPIRA WOMENS HEALTH INC COM 04537Y109 6,355 1,130,720 SH   SOLE   6,355 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 1,818 116,900 SH   SOLE   1,818 0 0
AUDACY INC CL A 05070N103 421 97,500 SH   SOLE   421 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 2,106 162,500 SH   SOLE   2,106 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 71 10,500 SH   SOLE   71 0 0
AVINGER INC COM 053734604 44 35,000 SH   SOLE   44 0 0
AVROBIO INC COM 05455M100 27 3,000 SH   SOLE   27 0 0
AXSOME THERAPEUTICS INC COM 05464T104 911 13,500 SH   SOLE   911 0 0
BELLEROPHON THERAPEUTICS INC COM NEW 078771300 121 25,000 SH   SOLE   121 0 0
BERKELEY LTS INC COM 084310101 538 12,000 SH   SOLE   538 0 0
BIOLINE RX LTD SPONSORED ADS 09071M205 78 27,500 SH   SOLE   78 0 0
BIONANO GENOMICS INC COM 09075F107 257 35,000 SH   SOLE   257 0 0
BIOXCEL THERAPEUTICS INC COM 09075P105 1,221 42,000 SH   SOLE   1,221 0 0
C3 AI INC CL A 12468P104 1 80 SH   SOLE   1 0 0
CARDIFF ONCOLOGY INC COM 14147L108 682 102,500 SH   SOLE   682 0 0
CASSAVA SCIENCES INC COM 14817C107 3,845 45,000 SH   SOLE   3,845 0 0
CELLECTAR BIOSCIENCES INC COM PAR 15117F500 259 217,500 SH   SOLE   259 0 0
CHAMPIONS ONCOLOGY INC COM NEW 15870P307 514 50,000 SH   SOLE   514 0 0
CHECKPOINT THERAPEUTICS INC COM 162828107 605 205,000 SH   SOLE   605 0 0
CLEARSIDE BIOMEDICAL INC COM 185063104 11,993 2,462,500 SH   SOLE   11,993 0 0
CLEVELAND-CLIFFS INC NEW COM 185899101 65 3,000 SH   SOLE   65 0 0
CLOVIS ONCOLOGY INC COM 189464100 70 12,000 SH   SOLE   70 0 0
COHERUS BIOSCIENCES INC COM 19249H103 90 6,500 SH   SOLE   90 0 0
COINBASE GLOBAL INC COM CL A 19260Q107 684 2,700 SH   SOLE   684 0 0
COLLPLANT BIOTECHNOLOGIES LT SHS NEW M2R51X116 160 7,500 SH   SOLE   160 0 0
CURE PHARMACEUTICAL HLDG CORP COM 23127P104 16 30,000 SH   SOLE   16 0 0
CURIS INC COM NEW 231269200 646 80,000 SH   SOLE   646 0 0
CYTEIR THERAPEUTICS INC COM 23284P103 2 90 SH   SOLE   2 0 0
CYTOSORBENTS CORP COM NEW 23283X206 265 35,000 SH   SOLE   265 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 1,351 158,500 SH   SOLE   1,351 0 0
ENLIVEX THERAPEUTICS LTD COM M4130Y106 735 82,500 SH   SOLE   735 0 0
ENTHUSIAST GAMING HOLDINGS INC COM 29385B109 238 40,000 SH   SOLE   238 0 0
ERYTECH PHARMA SPONSORED ADR 29604W108 10 2,000 SH   SOLE   10 0 0
ESPORTS ENTMT GROUP INC COM 29667K306 706 65,000 SH   SOLE   706 0 0
EZGO TECHNOLOGIES LTD SHS G5279F102 5 1,000 SH   SOLE   5 0 0
F5 NETWORKS INC COM 315616102 2,707 14,500 SH   SOLE   2,707 0 0
FORD MTR CO DEL COM 345370860 773 52,000 SH   SOLE   773 0 0
FORTE BIOSCIENCES INC COM 34962G109 541 16,071 SH   SOLE   541 0 0
FUBOTV INC COM 35953D104 8,606 268,000 SH   SOLE   8,606 0 0
GENETRON HOLDINGS LIMITED ADS 37186H100 152 7,500 SH   SOLE   152 0 0
GENOCEA BIOSCIENCES INC COM NEW 372427401 12 5,000 SH   SOLE   12 0 0
GORES HOLDINGS VI INC COM CL A 38286R105 1,605 99,000 SH   SOLE   1,605 0 0
HELIUS MED TECHNOLOGIES INC COM CL A NEW 42328V603 1,002 59,186 SH   SOLE   1,002 0 0
ICAD INC COM NEW 44934S206 3,844 222,000 SH   SOLE   3,844 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 1,453 69,200 SH   SOLE   1,453 0 0
IMMATICS N V COM N44445109 738 63,500 SH   SOLE   738 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 300 100,200 SH   SOLE   300 0 0
INHIBIKASE THERAPEUTICS INC COM COM 45719W106 2,450 875,000 SH   SOLE   2,450 0 0
INMODE LTD COM COM M5425M103 2,140 22,600 SH   SOLE   2,140 0 0
INSTIL BIO INC COM 45783C101 194 10,000 SH   SOLE   194 0 0
ISHARES SILVER TR ISHARES 46428Q109 872 36,000 SH   SOLE   872 0 0
JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105 440 14,500 SH   SOLE   440 0 0
KALA PHARMACEUTICALS INC COM 483119103 1,007 190,000 SH   SOLE   1,007 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 145 14,000 SH   SOLE   145 0 0
KAZIA THERAPEUTICS LIMITED SPONSORED ADR 48669G105 247 25,000 SH   SOLE   247 0 0
KINGSOFT CLOUD HLDGS LTD ADS 49639K101 153 4,500 SH   SOLE   153 0 0
KRYSTAL BIOTECH INC COM 501147102 1,298 19,075 SH   SOLE   1,298 0 0
LANDCADIA HOLDINGS III INC COM CL A 51476H100 403 32,500 SH   SOLE   403 0 0
LEAP THERAPEUTICS INC COM 52187K101 220 134,000 SH   SOLE   220 0 0
MARKER THERAPEUTICS INC COM 57055L107 1,172 420,000 SH   SOLE   1,116 0 0
MEDICENNA THERAPEUTICS CORP COM 58490H107 1,054 350,000 SH   SOLE   1,054 0 0
MODERNA INC COM 60770K107 1,058 4,500 SH   SOLE   1,058 0 0
MOGO INC COM COM 60800C109 373 47,500 SH   SOLE   373 0 0
MYOVANT SCIENCES LTD COM G637AM102 1,993 87,500 SH   SOLE   1,993 0 0
NATERA INC COM 632307104 2,941 25,900 SH   SOLE   2,941 0 0
NEKTAR THERAPEUTICS COM 640268108 2,772 161,500 SH   SOLE   2,772 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 2,207 239,000 SH   SOLE   2,207 0 0
NOVAVAX INC COM NEW 670002401 2,187 10,300 SH   SOLE   2,187 0 0
NUANCE COMMUNICATIONS INC COM 67020Y100 2,042 37,500 SH   SOLE   2,042 0 0
NVIDIA CORPORATION COM 67066G104 721 900 SH   SOLE   721 0 0
ONCOCYTE CORPORATION COM 68235C107 1,895 330,000 SH   SOLE   1,895 0 0
ONCTERNAL THERAPEUTICS INC COM 68236P107 1,710 360,000 SH   SOLE   1,710 0 0
OYSTER PT PHARMA INC COM 69242L106 542 31,500 SH   SOLE   542 0 0
PDS BIOTECHNOLOGY CORP COM 70465T107 565 45,000 SH   SOLE   565 0 0
PEABODY ENGR CORP COM 704551100 159 20,000 SH   SOLE   159 0 0
QUDIAN INC ADR 747798106 61 25,000 SH   SOLE   61 0 0
QUHUO LTD ADS 74841Q100 44 9,900 SH   SOLE   44 0 0
QUIDEL CORP COM 74838J101 782 6,100 SH   SOLE   782 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 1,784 12,600 SH   SOLE   1,784 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 964 140,000 SH   SOLE   964 0 0
RELMADA THERAPEUTICS INC COM 75955J402 791 24,700 SH   SOLE   791 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 607 31,000 SH   SOLE   607 0 0
ROCKET COS INC COM CL A 77311W101 420 21,700 SH   SOLE   420 0 0
SIO GENE THERAPIES INC COM 829399104 506 185,000 SH   SOLE   506 0 0
SQZ BIOTECHNOLOGIES CO COM 78472W104 109 7,500 SH   SOLE   109 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 35,319 231,600 SH   SOLE   35,319 0 0
SUPERIOR DRILLING PRODS INC COM 868153107 113 122,500 SH   SOLE   113 0 0
SURFACE ONCOLOGY INC COM 86877M209 1,272 170,500 SH   SOLE   1,272 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 287 52,500 SH   SOLE   287 0 0
TERADATA CORP COM 88076W103 550 11,000 SH   SOLE   550 0 0
TG THERAPEUTICS INC COM 88322Q108 2,134 55,000 SH   SOLE   2,134 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 2,902 172,750 SH   SOLE   2,902 0 0
TRACON PHARMACEUTICALS INC COM NEW 89237H209 185 28,500 SH   SOLE   185 0 0
TRANSMEDICS GROUP INC COM 89377M109 33 1,000 SH   SOLE   33 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 4,511 465,000 SH   SOLE   4,511 0 0
UNITED THERAPEUTICS CORP COM 91307C102 1,884 10,500 SH   SOLE   1,884 0 0
UNITY SOFTWARE INC COM 91332U101 3,306 30,100 SH   SOLE   3,306 0 0
UP FINTECH HOLDING LIMITED SPONSORED ADS 91531W106 739 25,500 SH   SOLE   739 0 0
UPSTART HLDGS INC COM 91680M107 3,098 24,800 SH   SOLE   3,098 0 0
VERTEX ENERGY INC COM 92534K107 139 10,500 SH   SOLE   139 0 0
VIKING THERAPEUTICS INC COM 92686J106 770 128,500 SH   SOLE   770 0 0
VISTAGEN THERAPEUTICS INC COM NEW 92840H202 315 100,000 SH   SOLE   315 0 0
YALLA GROUP LTD ADS 98459U103 270 13,500 SH   SOLE   270 0 0
ZOVIO INC COM 98979V102 78 30,000 SH   SOLE   78 0 0