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Stockholders' Equity - Summary of Stock Option Activity (Detail) - $ / shares
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Outstanding Beginning Balance, Number of Shares 1,389,816 1,317,402
Granted, Number of Shares 420,500 117,500
Canceled/Forfeited, Number of Shares (37,250) (45,086)
Outstanding Ending Balance, Number of Shares 1,773,066 1,389,816
Outstanding Beginning Balance, Weighted-Average Exercise Price Per Share $ 8.39 $ 9.09
Granted, Weighted-Average Exercise Price Per Share 2.38 2.07
Canceled/Forfeited, Weighted-Average Exercise Price Per Share 5.98 12.37
Outstanding Ending Balance, Weighted-Average Exercise Price Per Share 7.02 8.39
Exercise Price Per Share, Minimum 1.17 1.17
Exercise Price Per Share, Maximum 26.00 26.00
Outstanding, 2.08 — 26.00 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum   2.08
Exercise Price Per Share, Maximum   26.00
Granted, 1.17 — 2.71 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum   1.17
Exercise Price Per Share, Maximum   2.71
Canceled/Forfeited, 4.80 — 23.20 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum   4.80
Exercise Price Per Share, Maximum   23.20
Outstanding, 1.17 — 26.00 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum   1.17
Exercise Price Per Share, Maximum   $ 26.00
Granted, 1.65 — 2.62 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum 1.65  
Exercise Price Per Share, Maximum 2.62  
Canceled/Forfeited, 2.39 — 23.20 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum 2.39  
Exercise Price Per Share, Maximum 23.20  
Outstanding, 1.17 — 26.00 [Member]    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Exercise Price Per Share, Minimum 1.17  
Exercise Price Per Share, Maximum $ 26.00