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Net Loss per Share (Tables)
12 Months Ended
Dec. 31, 2020
Earnings Per Share [Abstract]  
Common Stock Excluded from Calculation of Diluted Earnings Per Share
The following common stock equivalents were excluded from the calculation of diluted net loss per share applicable to common stockholders for the periods indicated because including them would have had an anti-dilutive effect:
Years ended December 31,
202020192018
Stock options6,143,046 6,201,485 5,416,069 
Restricted stock units1,284,378 766,953 532,144 
Performance-based stock units— 72,046 169,031 
Employee Stock Purchase Plan shares46,439 49,418 32,304 
Total7,473,863 7,089,902 6,149,548