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Loss per Share (Tables)
3 Months Ended
Mar. 31, 2019
Earnings Per Share [Abstract]  
Common Stock Excluded from Calculation of Diluted Earnings Per Share
The following common stock equivalents were excluded from the calculation of diluted net loss per share applicable to common stockholders for the periods indicated because including them would have had an anti-dilutive effect:
Three Months Ended March 31,
20192018
Stock options6,482,873 6,104,808 
Restricted stock units709,162 405,646 
Employee stock purchase plan6,778 5,289 
Total common stock equivalents7,198,813 6,515,743