Collaboration Agreements - 2016 Agreement (Details) - 2016 Agreement	1 Months Ended
	May 31, 2016 Program special_case_extension	May 17, 2016 special_case_extension
Celgene
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of programs that may be designated for continued development for which development candidates have yet to be nominated	3
Celgene
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of cancer metabolism programs discovered under previous agreement, now governed by current agreement	2
Initial research term	4 years
Extension period	2 years
Number of allowable special case extensions | special_case_extension	4	4
Special case extension term	1 year