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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Income Statement [Abstract]        
Collaboration revenue - related party $ 8,411 $ 6,268 $ 16,822 $ 12,536
Operating expenses:        
Research and development 22,576 12,958 39,982 24,420
General and administrative 4,165 1,836 7,454 3,688
Total operating expenses 26,741 14,794 47,436 28,108
Loss from operations (18,330) (8,526) (30,614) (15,572)
Interest income 34 5 70 13
Loss before provision for income taxes (18,296) (8,521) (30,544) (15,559)
Provision for income taxes   (99)   (289)
Net loss (18,296) (8,620) (30,544) (15,848)
Cumulative preferred stock dividends   (1,798)   (3,595)
Net loss applicable to common stockholders $ (18,296) $ (10,418) $ (30,544) $ (19,443)
Net loss per share applicable to common stockholders - basic and diluted $ (0.54) $ (2.80) $ (0.94) $ (5.27)
Weighted-average number of common shares used in net loss per share applicable to common stockholders - basic and diluted 33,602,472 3,722,963 32,506,739 3,690,669