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INTANGIBLE ASSETS - Amortization of Intangible Assets (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Nov. 30, 2017
Finite-Lived Intangible Assets [Line Items]      
Accumulated Amortization $ (88,602) $ (68,952)  
Intangible assets finite-lived, net 157,200    
Intangible assets, gross (excluding goodwill) 245,802 255,643  
Intangible assets, net (excluding goodwill) $ 157,200 $ 186,691  
Chenodal Product Rights      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 16 years 16 years  
Gross Carrying Amount $ 67,849 $ 67,849  
Accumulated Amortization (24,451) (20,213)  
Intangible assets finite-lived, net $ 43,398 $ 47,636  
Thiola License      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 15 years 15 years  
Gross Carrying Amount $ 85,824 $ 70,009 $ 5,900
Accumulated Amortization (20,417) (14,523)  
Intangible assets finite-lived, net $ 65,407 $ 55,486  
Economic Interest - U.S. revenue Cholbam      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 10 years 10 years  
Gross Carrying Amount $ 75,900 $ 75,900  
Accumulated Amortization (36,071) (28,487)  
Intangible assets finite-lived, net $ 39,829 $ 47,413  
Economic Interest - International revenue Cholbam      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 10 years 10 years  
Gross Carrying Amount $ 7,544 $ 7,700  
Accumulated Amortization (3,585) (2,890)  
Intangible assets finite-lived, net $ 3,959 4,810  
Economic Interest - L-UDCA (acquired IPR&D)      
Finite-Lived Intangible Assets [Line Items]      
Indefinite-lived intangible assets   $ 25,500  
Ligand License      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 11 years 11 years  
Gross Carrying Amount $ 7,900 $ 7,900  
Accumulated Amortization (3,555) (2,397)  
Intangible assets finite-lived, net $ 4,345 $ 5,503  
Manchester Customer Relationships      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 10 years 10 years  
Gross Carrying Amount $ 403 $ 403  
Accumulated Amortization (232) (192)  
Intangible assets finite-lived, net $ 171 $ 211  
Manchester Trade Name      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 1 year 1 year  
Gross Carrying Amount $ 175 $ 175  
Accumulated Amortization (175) (175)  
Intangible assets finite-lived, net $ 0 $ 0  
Internal Use Software      
Finite-Lived Intangible Assets [Line Items]      
Useful Life 5 years 5 years  
Gross Carrying Amount $ 207 $ 207  
Accumulated Amortization (116) (75)  
Intangible assets finite-lived, net $ 91 $ 132