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ACCRUED EXPENSES (Tables)
12 Months Ended
Dec. 31, 2017
Payables and Accruals [Abstract]  
Schedule of accrued expenses
Accrued expenses consist of the following at December 31, 2017 and 2016 (in thousands):
 
2017
 
2016
Compensation related costs
$
7,749

 
$
7,441

Research and development
6,989

 
7,311

Government rebate reserves
5,883

 
6,967

Selling, general and administrative
3,896

 
3,333

Royalty/contingent consideration
6,429

 
5,766

Restructuring expenses
3,549

 
893

Miscellaneous accrued expenses
1,523

 
1,597

Total accrued expenses
$
36,018

 
$
33,308