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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Cash flows from operating activities:    
Net loss $ (24,492) $ (17,401)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation, amortization and write-off of property and equipment 1,167 1,024
Amortization and write-off of intangibles 437 775
Stock-based compensation 5,345 4,872
Changes in operating assets and liabilities:    
Trade accounts receivable 3,447 (1,952)
Other current assets (261) (482)
Other assets (148) 20
Accounts payable and other accrued liabilities (374) 373
Deferred revenue (1,225) (1,247)
Net cash used in operating activities (16,104) (14,018)
Cash flows from investing activities:    
Purchase of property and equipment (1,023) (1,424)
Capitalized patent costs (571) (625)
Maturity of marketable securities 30,179 41,231
Purchase of marketable securities (18,904) (27,631)
Net cash provided by investing activities 9,681 11,551
Cash flows from financing activities:    
Issuance of common stock, net of issuance costs 0 17,698
Exercise of stock options 1,064 793
Purchase of common stock (1,689) (2,063)
Net cash provided by (used in) financing activities (625) 16,428
Net increase (decrease) in cash and cash equivalents (7,048) 13,961
Cash and cash equivalents at beginning of period 40,823 11,638
Cash and cash equivalents at end of period 33,775 25,599
Supplemental disclosure of cash flow information:    
Cash received (paid) for income taxes, net 92 (29)
Supplemental schedule of non-cash investing activities:    
Property and equipment and patent costs in accounts payable (39) 249
Stock-based compensation capitalized to software and patent costs $ 130 $ 151