CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Operating Activities
Net loss	$ (42,715)	$ (123,873)
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities:
Depreciation and amortization expense	4,043	3,396
Amortization of debt issuance costs	650	503
Provision for expected credit losses	2,198	1,386
Accretion (amortization) of discount or premium on short-term investments	(434)	312
Stock-based compensation expense	22,039	21,194
Loss on extinguishment of debt	1,268	0
Acquired in-process research and development expenses	0	78,750
Other	52	94
Changes in operating assets and liabilities:
Accounts receivable, net	9,765	22,845
Inventories	3,157	(19,916)
Prepaid and other current assets	(4,104)	(5,208)
Other long-term assets	(236)	(386)
Accounts payable and accrued expenses	(3,369)	(919)
Employee-related liabilities	(1,654)	(210)
Deferred revenue	(372)	925
Operating leases and other current liabilities	883	2,895
Other long-term liabilities	833	(114)
Net cash used in operating activities	(7,996)	(18,326)
Investing Activities
Purchases of short-term investments	(84,249)	(109,115)
Proceeds from maturities and redemptions of short-term investments	83,650	163,110
Purchases of property and equipment	(4,457)	(8,828)
Acquisitions, including in-process research and development, net of cash acquired	0	(69,496)
Purchases of intangible assets and strategic investments	0	(2,000)
Net cash used in investing activities	(5,056)	(26,329)
Financing Activities
Proceeds from issuance of convertible senior notes due 2029, net of $9,400 debt issuance costs	306,850	0
Repurchase of $246,740 principal amount of convertible senior notes due 2025	(246,123)	0
Payment for capped call transactions related to convertible senior notes due 2029	(15,813)	0
Repurchase and retirement of common stock	(30,000)
Proceeds from issuance of common stock under Company stock plans, net of cash used to settle withholding taxes on vested restricted stock	(1,511)	(541)
Other financing activities	183	0
Net cash provided by (used in) financing activities	13,586	(541)
Effect of foreign exchange rate changes on cash	(423)	441
Net increase (decrease) in cash and cash equivalents	111	(44,755)
Cash and cash equivalents at beginning of period	58,868	172,517
Cash and cash equivalents at end of period	58,979	127,762
Supplemental disclosures of cash flow information
Income taxes paid	269	369
Supplemental schedule of non-cash investing and financing activities
Operating lease right-of-use assets obtained in exchange for operating lease obligations	2,294	0
Purchases of property and equipment included in accounts payable	3,214	4,071
Intangible costs in accounts payable	$ 0	$ 515