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Collaboration and Licensing Agreements - Narrative (Details)
$ in Thousands, $ in Millions, ¥ in Billions
1 Months Ended 3 Months Ended 9 Months Ended 71 Months Ended
Mar. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Nov. 30, 2017
USD ($)
Jun. 30, 2015
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2023
CAD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
Oct. 31, 2023
USD ($)
Sep. 30, 2023
JPY (¥)
Jul. 31, 2023
USD ($)
Apr. 30, 2023
USD ($)
Oct. 31, 2022
USD ($)
Apr. 30, 2022
USD ($)
payment_tranche
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues         $ 56,391 $ 4,986 $ 90,093   $ 7,980              
Licensing revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues         32,014 9 32,790   23              
Product supply revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues         2,092 92 5,354   1,058              
2017 KKC Agreement | Licensing revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues           0     0              
2017 KKC Agreement | Product supply revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues         2,100 83 5,400   1,000              
Fosun Agreement | Licensing revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues           0     0              
Knight Agreement | Licensing revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues         0 0 0   0              
KKC | 2017 KKC Agreement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Upfront license fees     $ 30,000                          
Potential development milestones     $ 55,000                          
Total revenues                   $ 35,000            
Potential commercialization milestones         57,000   57,000     57,000   ¥ 8.5        
Fee receivable for reduction in royalty rate                               $ 40,000
Number of payment tranches for fee receivable for reduction in royalty rate | payment_tranche                               2
KKC | 2017 KKC Agreement | Licensing revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Revenue to be received         20,000   20,000     20,000            
Proceeds from milestone payments         30,000   30,000     30,000         $ 35,000  
Fosun Pharma | Fosun Agreement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Potential development milestones         5,000   5,000     5,000            
Proceeds from milestone payments                         $ 2,000      
Upfront payment received   $ 12,000                            
Potential development and commercialization milestones             $ 113,000                  
Threshold percentage of net sales for tiered royalties             20.00% 20.00%                
Fosun Pharma | Fosun Agreement | Subsequent event                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Proceeds from milestone payments                     $ 3,000          
Knight | Knight Agreement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Potential development milestones         700   $ 700     700            
Upfront payment received $ 2,300                              
Potential development and commercialization milestones             16,400 $ 22.2                
METiS Therapeutics Inc | Licensing revenue                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Total revenues         800   800                  
Revenue to be received                           $ 800    
Proceeds from milestone payments                           $ 243,000    
AstraZeneca | AZ Termination Agreement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Percentage of royalty revenue       10.00%                        
Percentage of non-royalty revenue       20.00%                        
Maximum potential payment per agreement       $ 75,000                        
Aggregate cost of revenue recognized         23,900   23,900     23,900            
Aggregate amount paid         18,300   18,300     $ 18,300            
Cost of revenue         $ 5,700 $ 500 $ 8,700   $ 800