Accrued and Other Liabilities - Schedule of Accrued Liabilities and Other Liabilities (Detail) - USD ($) $ in Thousands	Jun. 30, 2017	Dec. 31, 2016
Payables and Accruals [Abstract]
Accrued clinical and non-clinical expenses	$ 7,271	$ 6,694
Accrued contract manufacturing	2,580	2,705
Accrued professional and consulting services	370	322
Other	855	684
Accrued liabilities and other liabilities	$ 11,076	$ 10,405	[1]

[1] Derived from the audited financial statements included in the Company's Annual Report on Form 10-K for the year ended December 31, 2016.