Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of Reconciliation of the U.S. Statutory Income Tax Rate to the Company's Effective Tax Rate

A reconciliation of the U.S. statutory income tax rate to the Company’s effective tax rate is as follows:

	December 31,
	2022		2021
Federal income tax (benefit) at statutory rate	(21.0)	%	(21.0)	%
Change in state tax rate	(0.5)	%	0.9	%
Permanent items	0.1	%	0.1	%
Prior period adjustments	(3.6)	%	—	%
Other	—	%	0.4	%
Change in valuation allowance	25.0	%	19.6	%
Effective income tax rate	0.0	%	0.0	%

Summary of Income Tax Contingencies

	December 31,
	2022		2021
	(in thousands)
Balance at January 1	$	2,099	$	2,606
Reductions for tax positions of prior year	—		(507)
Balance at December 31	2,099		2,099

Schedule of Significant Components of the Company's Deferred Tax Assets

Significant components of the Company’s deferred tax assets are summarized in the table below:

	December 31,
	2022		2021
	(in thousands)
Deferred tax assets:
Federal and state operating loss carryforwards	$	242,584	$	219,237
Equity compensation	26,243		22,735
Capitalized research and development	26,480		—
R&D tax credits, net of reserves	18,887		18,887
Disallowed interest	29,979		16,146
Temporary differences	8,340		7,695
Total deferred tax assets	352,513		284,700
Deferred tax liabilities:
Other	(400)		(546)
Total deferred tax liabilities	(400)		(546)
Valuation allowance	(352,113)		(284,154)
Net deferred tax assets	$	—	$	—