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Note C - Debt Obligations (Details Textual) - USD ($)
6 Months Ended
Jun. 30, 2016
Feb. 09, 2016
Jun. 02, 2014
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2013
Deerfield Facility Agreement [Member] | Term Notes [Member]            
Proceeds from Secured Notes Payable     $ 15,000,000      
Deerfield Facility Agreement [Member] | Deerfield Convertible Notes [Member]            
Proceeds from Secured Notes Payable     $ 10,000,000      
Debt Instrument, Convertible, Conversion Price     $ 5.85      
Deerfield Facility Agreement [Member] | Series D Redeemable Convertible Preferred Stock [Member]            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     14,423,076      
Own-share Lending Arrangement, Shares, Issued     1,923,077      
Mandatorily Redeemable Preferred Stock, Fair Value Disclosure     $ 1,500,000      
Deerfield Facility Agreement [Member] | Deerfield Warrant [Member] | IPO [Member]            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     1,923,077      
Deerfield Facility Agreement [Member] | Deerfield Warrant [Member]            
Class of Warrant or Right, Exercise Price of Warrants or Rights     $ 0.78      
Deerfield Facility Agreement [Member] | IPO [Member]            
Reclassification of Common Stock Shares     256,410      
Deerfield Facility Agreement [Member]            
Line of Credit Facility, Maximum Borrowing Capacity     $ 60,000,000      
Line of Credit Facility, Interest Rate at Period End     9.75%      
Second Line of Credit Agreement [Member] | Wells Fargo Bank, N.A. [Member] | Prime Rate [Member]            
Debt Instrument, Basis Spread on Variable Rate       9.99%    
Second Line of Credit Agreement [Member] | Wells Fargo Bank, N.A. [Member]            
Line of Credit Facility, Maximum Borrowing Capacity $ 100,000     $ 100,000    
Debt Instrument, Interest Rate, Stated Percentage 13.49%     13.49%    
Line of Credit Facility, Remaining Borrowing Capacity $ 73,000     $ 73,000    
First Line of Credit Agreement [Member] | Wells Fargo Bank, N.A. [Member]            
Line of Credit Facility, Maximum Borrowing Capacity         $ 50,000  
Third Line of Credit Agreement [Member] | City National Bank of Florida [Member] | Prime Rate [Member]            
Debt Instrument, Interest Rate, Stated Percentage 2.47%     2.47%    
Debt Instrument, Basis Spread on Variable Rate 2.00%          
Third Line of Credit Agreement [Member] | City National Bank of Florida [Member]            
Line of Credit Facility, Maximum Borrowing Capacity $ 1,100,000     $ 1,100,000    
Long-term Line of Credit $ 0     $ 0    
2021 Notes [Member]            
Debt Instrument, Convertible, Conversion Price   $ 17.11        
Debt Instrument, Face Amount   $ 86,250,000        
Debt Instrument, Interest Rate, Stated Percentage   5.50%        
Proceeds from Debt, Net of Issuance Costs   $ 82,800,000        
Repayments of Long-term Debt   18,600,000        
Debt Instrument, Sinking Fund Payment   $ 0        
Debt Conversion, Converted Instrument, Shares Issued   58.4454        
Debt Conversion, Original Debt, Amount   $ 1,000        
Debt Instrument Repurchase Price Equal to Percentage of Principal Amount   100.00%        
Debt Instrument Conversion Term   1 year        
Series D Redeemable Convertible Preferred Stock [Member]            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 15,499,324     15,499,324   1,079,453