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Note H - Fair Value of Financial Instruments (Tables)
6 Months Ended
Jun. 30, 2016
Notes Tables  
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
   
Balance at
June 30
,
2016
   
Quoted Prices
in Active
Markets for
Identical Assets
(Level 1)
   
Significant
Other
Observable
Inputs
(Level 2)
   
Significant
Unobservable
Inputs
(Level 3)
 
Underwri
ter Warrant liability
  $ 53     $     $     $ 53  
Deerfield Warrant liability
    5,404                   5,404  
Embedded Put Option
    557                   557  
Fundamental change and make-whole interest provisions embedded in 2021 Notes
    29                   29  
Total liabilities
  $ 6,043     $     $     $ 6,043  
Trading securities:
                               
Certificates of deposit
    11,911       11,911              
Government bonds
    62,073       62,073              
Total assets
  $ 73,984     $ 73,984     $     $  
   
Balance at
December 31,
2015
   
Quoted Prices
in Active
Markets for
Identical Assets
(Level 1)
   
Significant
Other
Observable
Inputs
(Level 2)
   
Significant
Unobservable
Inputs
(Level 3)
 
Underwriter Warrant liability
  $ 3,877     $     $     $ 3,877  
Deerfield Warrant liability
    33,750                   33,750  
Embedded Put Option
    212                   212  
Total liabilities
  $ 37,839     $     $     $ 37,839  
Trading securities:
                               
Certificates of deposit
    8,951       8,951              
Government bonds
    10,051       10,051              
Total assets
  $ 19,002     $ 19,002     $     $  
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
   
Three Months Ended
June 30,
   
Six Months Ended
June 30,
 
   
2016
   
2015
   
2016
   
2015
 
Balance at beginning of period
  $ 27,479     $ 17,728     $ 37,839     $ 15,966  
  Reclassification of 2013 Convertible Notes           (1,110 )           (1,110 )
Exercise of warrants
    (673 )           (755 )      
Adjustment to fair value
    (20,763 )     22,661       (31,041 )     24,423  
Balance at end of period
  $ 6,043     $ 39,279     $ 6,043     $ 39,279