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Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
3 Months Ended 83 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Mar. 31, 2014
Operating activities      
Net loss $ (6,980) $ (3,548) $ (93,489)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 123 157 2,631
Issuances of common stock for technology     57
Stock-based compensation 871 75 3,194
Amortization of discounts 8 18 543
Noncash interest expense 10 22 1,179
Deferred rent (9) (59) 179
Deferred revenue   (21)  
Stock-based milestone charges and change in fair value of exchangeable shares 375 105 3,693
Change in fair value of preferred stock warrants   (12) (35)
Loss on disposal of assets     135
Loss on extinguishment of debt     332
Changes in operating assets and liabilities:      
Prepaid expenses and other current assets 304 49 (1,673)
Accounts payable and accrued expenses 43 (719) 3,890
Net cash used in operating activities (5,255) (3,933) (79,364)
Investing activities      
Purchase of property and equipment (398) (7) (4,059)
Proceeds from sale of property and equipment     208
Restricted cash     (122)
Net cash used in investing activities (398) (7) (3,973)
Financing activities      
Issuance of common stock, net of repurchases and issuance costs (2)   292
Repurchase of common stock for cash     (7)
Proceeds from initial public offering, net of offering     40,480
Issuance of convertible promissory notes     32,236
Proceeds from long-term debt     6,400
Payments on long-term debt (500) (500) (6,829)
Issuance of preferred stock for cash, net of offering costs     58,646
Net cash (used in) provided by financing activities (502) (500) 131,218
Net change in cash and cash equivalents (6,155) (4,440) 47,881
Cash and cash equivalents at beginning of the period 54,036 9,087  
Cash and cash equivalents at end of the period $ 47,881 $ 4,647 $ 47,881