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Stockholders' Equity - Equity Offerings (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Dec. 14, 2015
Jan. 31, 2017
Mar. 31, 2017
Dec. 31, 2016
Equity Offerings        
Common stock, shares authorized (in shares)     100,000,000 100,000,000
Preferred stock, shares authorized (in shares)     5,000,000 5,000,000
Common stock, par value (in dollars per share)     $ 0.001 $ 0.001
Issuance of common stock, net of issuance costs     $ 6,833  
Maximum        
Equity Offerings        
Common stock, par value (in dollars per share) $ 0.001      
At Market Sales Facility        
Equity Offerings        
Issuance of common stock, net of issuance costs (in shares)   1,081,550   4,815,491
Issuance of common stock, net of issuance costs   $ 6,800   $ 32,100
Remaining amount available     $ 34,900  
At Market Sales Facility | Maximum        
Equity Offerings        
Offering price $ 75,000      
Commission (as percent) 3.00%      
At Market Sales Facility | Weighted-average        
Equity Offerings        
Offering price (in dollars per share)   $ 6.50   $ 6.865