Property and Equipment, net (Tables)

12 Months Ended

Dec. 31, 2017

Property, Plant and Equipment [Abstract]

Schedule of property and equipment

Property and equipment consisted of the following (in thousands):

	Estimated Useful	December 31,
	Life in Years	2017			2016
Laboratory equipment	5	$	—		$	1,935
Computers and software	3 - 5	749			521
Office equipment and furniture	5	872			314
Manufacturing equipment	5	242			242
Leasehold improvements	5 - 10	4,824			2,150
Leased assets	5	59			32
Total property and equipment		6,746			5,194
Less accumulated depreciation and amortization		(2,941		)	(4,135		)
Property and equipment, net		$	3,805		$	1,059